DNA hypomethylation caused by Lsh deletion promotes erythroleukemia development
نویسندگان
چکیده
منابع مشابه
Hypomethylation of DNA during differentiation of friend erythroleukemia cells
DNA from mammalian cells has been shown to contain significant amounts of 5-methyl cytosine resulting from enzymatic transfer of methyl groups from s-adenosylmethionine to cytosine residues in the DNA polymer. The function of this modification is not known. We have found that DNA synthesized during chemically induced differentiation of friend erythroleukemia cells is hypomethylated, as measured...
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ژورنال
عنوان ژورنال: Epigenetics
سال: 2008
ISSN: 1559-2294,1559-2308
DOI: 10.4161/epi.3.3.6252